Journal of Preventive, Aging, & Longevity Medicine

PHYSICIAN-AUTHORED · MON, OCT 5, 2026

Latest Articles48 Clinical Articles
What Is Healthspan Medicine? A Physician’s Framework for Evidence-Based Proactive Prevention
THE HEALTHSPAN CLIMATE5 min

What Is Healthspan Medicine? A Physician’s Framework for Evidence-Based Proactive Prevention

What is healthspan medicine? A physician breaks down evidence-based proactive prevention, how it differs from commercial longevity hype, and the 3 pillars of delaeMD.

delaeMD Clinical Team · Aug 9, 2026

The Health Benefits of Creatine: Muscle, Brain, and Bioenergetics
LIFESTYLE MEDICINE5 min

The Health Benefits of Creatine: Muscle, Brain, and Bioenergetics

Is creatine just for athletes? A physician breaks down the evidence for creatine on muscle mass, cognitive function, kidney lab testing (combined creatinine–cystatin C eGFR), and simple daily dosing.

delaeMD Clinical Team · Aug 7, 2026

The 6 Core Movements of Resistance Training: A Physician’s Blueprint for Longevity and Movement Quality
LIFESTYLE MEDICINE7 min

The 6 Core Movements of Resistance Training: A Physician’s Blueprint for Longevity and Movement Quality

Want to build functional strength while protecting your joints? A physician breaks down the 6 core movement patterns, free weights vs. machines, and joint-friendly exercise variations.

delaeMD Clinical Team · Aug 7, 2026

The Fasting-Mimicking Diet: Science, Mechanisms, and Clinical Evidence
LIFESTYLE MEDICINE6 min

The Fasting-Mimicking Diet: Science, Mechanisms, and Clinical Evidence

Can you get the cellular benefits of fasting while still eating food? A physician breaks down the Fasting-Mimicking Diet, clinical evidence, the protein debate, and safety guidelines.

delaeMD Clinical Team · Aug 6, 2026

When Should You Start a Gerotherapeutic? The Timing Paradox in Longevity Medicine
GEROMEDICINE5 min

When Should You Start a Gerotherapeutic? The Timing Paradox in Longevity Medicine

When should you start a gerotherapeutic? A physician breaks down antagonistic pleiotropy, dosing nuances, why starting too early carries real trade-offs, and the middle-age hypothesis.

delaeMD Clinical Team · Aug 5, 2026

Biological Age Tests and Epigenetic Clocks: What the Science Shows (And What It Can't Tell You)
GEROMEDICINE5 min

Biological Age Tests and Epigenetic Clocks: What the Science Shows (And What It Can't Tell You)

Are direct-to-consumer biological age tests worth it? A physician breaks down how epigenetic clocks work, what the science proves, and why they currently lack clinical utility.

delaeMD Clinical Team · Aug 4, 2026

Why Cardiorespiratory Fitness Is One of the Strongest Predictors of Healthspan (And How to Train It)
LIFESTYLE MEDICINE5 min

Why Cardiorespiratory Fitness Is One of the Strongest Predictors of Healthspan (And How to Train It)

Why is cardiorespiratory fitness a key longevity metric? A physician breaks down testing methods, accuracy, the evidence-backed 4x4 protocol, and exercise-drug interactions.

delaeMD Clinical Team · Aug 4, 2026

Decoding the 2026 Cholesterol Guidelines: Why "Lower for Longer" Is the Essential Strategy for Cardiovascular Health
DISEASE-SPECIFIC PREVENTION5 min

Decoding the 2026 Cholesterol Guidelines: Why "Lower for Longer" Is the Essential Strategy for Cardiovascular Health

What do the updated 2026 cholesterol guidelines mean for your heart? A physician breaks down ApoB, PREVENT risk tiers, Lp(a), and the "lower for longer" strategy.

delaeMD Clinical Team · Aug 2, 2026

The Protein Paradox: Balancing Longevity Science with Functional Muscle Preservation
LIFESTYLE MEDICINE5 min

The Protein Paradox: Balancing Longevity Science with Functional Muscle Preservation

Restrict protein for longevity or increase it to preserve muscle? A physician breaks down the protein paradox, human cohort data, and evidence-based intake guidelines.

delaeMD Clinical Team · Aug 2, 2026

Therapeutic Plasma Exchange and Plasma Dilution: Separating Geroscience from Commercial Hype
GEROMEDICINE6 min

Therapeutic Plasma Exchange and Plasma Dilution: Separating Geroscience from Commercial Hype

Is plasma exchange a true geroscience breakthrough or commercial hype? A physician breaks down neutral plasma dilution, the AMBAR trial, epigenetic clock data in healthy adults, and safety considerations.

delaeMD Clinical Team · Aug 2, 2026

Metformin as a Gerotherapeutic: Science, Promise, and Clinical Realities
GEROMEDICINE6 min

Metformin as a Gerotherapeutic: Science, Promise, and Clinical Realities

Is metformin a true anti-aging drug or a metabolic medication? A physician breaks down the science, mouse ITP trials, exercise interaction data, and long-term mortality studies.

delaeMD Clinical Team · Jul 31, 2026

Beyond the Basic Panel: 5 Advanced Lab Tests for Proactive Cardiovascular and Metabolic Health
DISEASE-SPECIFIC PREVENTION5 min

Beyond the Basic Panel: 5 Advanced Lab Tests for Proactive Cardiovascular and Metabolic Health

Looking to go beyond standard bloodwork? A physician breaks down 5 advanced lab tests—including ApoB, Lp(a), and hs-CRP—that provide deeper insights into long-term health.

delaeMD Clinical Team · Jul 31, 2026

Full-Body MRIs for Cancer Screening: Promises, Pitfalls, and How to Decide
DISEASE-SPECIFIC PREVENTION6 min

Full-Body MRIs for Cancer Screening: Promises, Pitfalls, and How to Decide

Thinking about getting a full-body MRI? A physician breaks down the pros, cons, false-positive risks, and why working with an independent doctor is essential before screening.

delaeMD Clinical Team · Jul 31, 2026

Why Proactive Healthspan Care Is the Next Essential Frontier in Medicine
THE HEALTHSPAN CLIMATE5 min

Why Proactive Healthspan Care Is the Next Essential Frontier in Medicine

Why is proactive health care so hard to access in traditional primary care? A physician breaks down the systemic limits of reactive medicine, the need for standardized healthspan care, and how targeted prevention protects long-term health.

delaeMD Clinical Team · Jul 30, 2026

GLP-1 RAs as Gerotherapeutics: Cardiometabolic Breakthrough or True Anti-Aging Therapy?
GEROMEDICINE5 min

GLP-1 RAs as Gerotherapeutics: Cardiometabolic Breakthrough or True Anti-Aging Therapy?

Are GLP-1 RAs like semaglutide true gerotherapeutics? A physician breaks down the evidence for inflammation reduction, cardiovascular protection, muscle quality nuances, and clinical protocols.

delaeMD Clinical Team · Jul 28, 2026

The NAD+ Paradox: Why Higher Blood Levels Don't Automatically Mean Better Healthspan
LIFESTYLE MEDICINE4 min

The NAD+ Paradox: Why Higher Blood Levels Don't Automatically Mean Better Healthspan

Do NMN supplements and NAD+ drips live up to the hype? A physician breaks down the human trial evidence, metabolic considerations, and how exercise naturally boosts cellular NAD+ machinery.

delaeMD Clinical Team · Jul 28, 2026

The $5,000 Healthspan Audit: 5 Overpriced Trends to Skip (and 3 Foundations That Actually Work)
THE HEALTHSPAN CLIMATE6 min

The $5,000 Healthspan Audit: 5 Overpriced Trends to Skip (and 3 Foundations That Actually Work)

Investing in proactive health? A physician evaluates five popular wellness trends (from unapproved peptides to unscreened MRIs) and highlights the three evidence-based foundations that actually protect your healthspan.

delaeMD Clinical Team · Jul 27, 2026

Rapamycin: The Preclinical Evidence, Human Studies, and Clinical Unknowns
GEROMEDICINE5 min

Rapamycin: The Preclinical Evidence, Human Studies, and Clinical Unknowns

Rapamycin is heavily discussed in geroscience, but what do human trials actually show? A physician breaks down mTOR biology, the ITP mouse studies, PEARL trial results, and key safety risks.

delaeMD Clinical Team · Jul 26, 2026

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