Evidence-Based Clinical Practice · Peer-Informed Research
Journal of Healthspan Medicine & Clinical Prevention
Physician-authored analysis of clinical trials, biomarker protocols, cardiometabolic health, and proactive disease prevention.
Why Healthspan Medicine Must Become a Recognized Medical Specialty
Why is primary care constrained in proactive prevention? A physician breaks down why healthspan medicine must become a recognized specialty, bridging evidence-based cardiology, exercise physiology, and geroscience.
SGLT2 Inhibitors as Gerotherapeutics: From Diabetes Medications to Longevity Candidates
Can diabetes drugs slow biological aging? A physician breaks down SGLT2 inhibitors, their preclinical lifespan data, hallmarks of aging, and human clinical trials.
From Bench to Bedside: How We Safely Evaluate Gerotherapeutics in Clinical Practice
How do physicians evaluate anti-aging drugs? A physician breaks down the clinical evidence for GLP-1s, SGLT2 inhibitors, Rapamycin, Metformin, and Fasting-Mimicking Diets in healthspan practice.
What Is Healthspan Medicine? A Physician’s Framework for Evidence-Based Proactive Prevention
What is healthspan medicine? A physician breaks down evidence-based proactive prevention, how it differs from commercial longevity hype, and the 3 pillars of delaeMD.
The Health Benefits of Creatine: Muscle, Brain, and Bioenergetics
Is creatine just for athletes? A physician breaks down the evidence for creatine on muscle mass, cognitive function, kidney lab testing (combined creatinine–cystatin C eGFR), and simple daily dosing.
The 6 Core Movements of Resistance Training: A Physician’s Blueprint for Longevity and Movement Quality
Want to build functional strength while protecting your joints? A physician breaks down the 6 core movement patterns, free weights vs. machines, and joint-friendly exercise variations.
The Fasting-Mimicking Diet: Science, Mechanisms, and Clinical Evidence
Can you get the cellular benefits of fasting while still eating food? A physician breaks down the Fasting-Mimicking Diet, clinical evidence, the protein debate, and safety guidelines.
When Should You Start a Gerotherapeutic? The Timing Paradox in Longevity Medicine
When should you start a gerotherapeutic? A physician breaks down antagonistic pleiotropy, dosing nuances, why starting too early carries real trade-offs, and the middle-age hypothesis.
Biological Age Tests and Epigenetic Clocks: What the Science Shows (And What It Can't Tell You)
Are direct-to-consumer biological age tests worth it? A physician breaks down how epigenetic clocks work, what the science proves, and why they currently lack clinical utility.
Why Cardiorespiratory Fitness Is One of the Strongest Predictors of Healthspan (And How to Train It)
Why is cardiorespiratory fitness a key longevity metric? A physician breaks down testing methods, accuracy, the evidence-backed 4x4 protocol, and exercise-drug interactions.
Decoding the 2026 Cholesterol Guidelines: Why "Lower for Longer" Is the Essential Strategy for Cardiovascular Health
What do the updated 2026 cholesterol guidelines mean for your heart? A physician breaks down ApoB, PREVENT risk tiers, Lp(a), and the "lower for longer" strategy.
The Protein Paradox: Balancing Longevity Science with Functional Muscle Preservation
Restrict protein for longevity or increase it to preserve muscle? A physician breaks down the protein paradox, human cohort data, and evidence-based intake guidelines.
Therapeutic Plasma Exchange and Plasma Dilution: Separating Geroscience from Commercial Hype
Is plasma exchange a true geroscience breakthrough or commercial hype? A physician breaks down neutral plasma dilution, the AMBAR trial, epigenetic clock data in healthy adults, and safety considerations.
Metformin as a Gerotherapeutic: Science, Promise, and Clinical Realities
Is metformin a true anti-aging drug or a metabolic medication? A physician breaks down the science, mouse ITP trials, exercise interaction data, and long-term mortality studies.
Beyond the Basic Panel: 5 Advanced Lab Tests for Proactive Cardiovascular and Metabolic Health
Looking to go beyond standard bloodwork? A physician breaks down 5 advanced lab tests—including ApoB, Lp(a), and hs-CRP—that provide deeper insights into long-term health.
Full-Body MRIs for Cancer Screening: Promises, Pitfalls, and How to Decide
Thinking about getting a full-body MRI? A physician breaks down the pros, cons, false-positive risks, and why working with an independent doctor is essential before screening.
Why Proactive Healthspan Care Is the Next Essential Frontier in Medicine
Why is proactive health care so hard to access in traditional primary care? A physician breaks down the systemic limits of reactive medicine, the need for standardized healthspan care, and how targeted prevention protects long-term health.
GLP-1 RAs as Gerotherapeutics: Cardiometabolic Breakthrough or True Anti-Aging Therapy?
Are GLP-1 RAs like semaglutide true gerotherapeutics? A physician breaks down the evidence for inflammation reduction, cardiovascular protection, muscle quality nuances, and clinical protocols.