Journal of Preventive, Aging, & Longevity Medicine
PHYSICIAN-AUTHORED · MON, OCT 5, 2026
DISEASE-SPECIFIC PREVENTION
Preventing Osteoporosis: How Middle-Aged Adults with Osteopenia Can Protect Bone Density
Diagnosed with osteopenia? A physician breaks down the LIFTMOR trial, heavy axial resistance loading, impact drills, and dietary calcium strategies to preserve bone density.
DISEASE-SPECIFIC PREVENTION
Is Whole Genome Sequencing Worth It for Preventive Health? A Physician's Guide
Is whole genome sequencing worth it for preventive health? A physician breaks down WGS technology, polygenic risk scores, GINA insurance laws, and clinical utility.
GEROMEDICINE
Rapamycin in Human Clinical Trials: What the Evidence Actually Shows
Does rapamycin actually slow aging in humans? A physician breaks down mTOR biology, the PEARL trial, immune rejuvenation data, and the side effects of off-label use.
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A physician-signed analysis of your 10- and 30-year disease risk.
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Lifestyle Medicine
Evidence-based physician writing on nutrition, training, sleep, and the daily inputs that move long-term health outcomes.
LIFESTYLE MEDICINEAug 19, 2026
The Science of Sleep Supplements: What Clinical Research Actually Supports
Which sleep supplements actually work? A physician breaks down the clinical research, mechanisms, and evidence-based dosages for melatonin, glycine, L-theanine, and magnesium.
LIFESTYLE MEDICINEAug 18, 2026
Is Zone 2 Cardio Over-Hyped? What the Science Really Says About Aerobic vs. High-Intensity Training
Is Zone 2 training really the holy grail of cardiovascular fitness? A physician breaks down the science of Zone 2 vs. HIIT, VO2 max, and how to balance your training.
LIFESTYLE MEDICINEAug 17, 2026
The Accuracy of Wearable Health Devices: A Clinician’s Guide to the Data
How accurate is your Apple Watch, Oura Ring, or Whoop? A physician explains the science of wearable accuracy, precision, HRV, sleep stages, and clinical utility.
LIFESTYLE MEDICINEAug 7, 2026
The Health Benefits of Creatine: Muscle, Brain, and Bioenergetics
Is creatine just for athletes? A physician breaks down the evidence for creatine on muscle mass, cognitive function, kidney lab testing (combined creatinine–cystatin C eGFR), and simple daily dosing.
Disease-Specific Prevention
Clinical guidance on preventing cardiovascular disease, metabolic disease, cancer, and other major drivers of early mortality.
DISEASE-SPECIFIC PREVENTIONAug 20, 2026
Lean Insulin Resistance: Why Normal-Weight Individuals Develop Type 2 Diabetes
Can you be thin and have type 2 diabetes? A physician explains lean insulin resistance, the personal fat threshold, the Asian phenotype, and how to manage normal-weight diabetes.
DISEASE-SPECIFIC PREVENTIONAug 15, 2026
Coronary Artery Calcium (CAC) Scans: Refining Cardiovascular Risk with Direct Imaging
What does your coronary calcium score mean? A physician explains how CAC scans work, what Agatston score categories indicate, radiation safety, cost, and differences from CCTA.
DISEASE-SPECIFIC PREVENTIONAug 14, 2026
Why Prevention Is Our Most Powerful Weapon Against Alzheimer’s Disease
Can Alzheimer's disease be prevented? A physician breaks down why current medications are limited and details evidence-based lifestyle, vascular, and metabolic strategies to protect brain health.
DISEASE-SPECIFIC PREVENTIONAug 13, 2026
Spotting Insulin Resistance Early: Beyond Fasting Glucose and HbA1c
Why do standard blood sugar labs miss early insulin resistance? A physician breaks down HOMA-IR, fasting insulin, CGMs, and early metabolic screening strategies.
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The Clinical
Dispatch
Physician-authored articles on healthspan and preventive medicine.
With Michael Leone, MD
Geromedicine
How aging biology, biomarkers, and geroscience research translate into practical clinical decisions today.
GEROMEDICINEAug 17, 2026
Senolytics in Geroscience: Can Clearing "Zombie Cells" Improve Human Healthspan?
Can clearing senescent cells slow biological aging? A physician explores the mechanisms, clinical trials, benefits, and risks of senolytics in geroscience.
GEROMEDICINEAug 14, 2026
The Whack-a-Mole Problem in Modern Medicine: Why the Future of Healthcare Depends on Geroscience
Why does modern medicine treat diseases in isolation? A physician explains the geroscience hypothesis, morbidity compression, and why funding basic aging biology is essential.
GEROMEDICINEAug 11, 2026
SGLT2 Inhibitors as Gerotherapeutics: From Diabetes Medications to Longevity Candidates
Can diabetes drugs slow biological aging? A physician breaks down SGLT2 inhibitors, their preclinical lifespan data, hallmarks of aging, and human clinical trials.
GEROMEDICINEAug 10, 2026
From Bench to Bedside: How We Safely Evaluate Gerotherapeutics in Clinical Practice
How do physicians evaluate anti-aging drugs? A physician breaks down the clinical evidence for GLP-1s, SGLT2 inhibitors, Rapamycin, Metformin, and Fasting-Mimicking Diets in healthspan practice.
The Healthspan Climate
Perspective on the healthcare system, diagnostics access, and the shifting landscape of preventive medicine.
THE HEALTHSPAN CLIMATEAug 22, 2026
DTC "Shotgun" Lab Panels: The Flawed Science of 100-Biomarker Testing
Are 100-biomarker direct-to-consumer blood tests worth it? A physician explains the math of false positives, diagnostic cascades, and why targeted testing is superior to shotgun panels.
THE HEALTHSPAN CLIMATEAug 19, 2026
Compressing Morbidity: How Healthspan Medicine and Geromedicine Protect Our Final Decades
Why is modern healthcare failing our final years? A physician explains the compression of morbidity, the three physiological reserves, and how geromedicine targets biological aging.
THE HEALTHSPAN CLIMATEAug 12, 2026
Why Healthspan Medicine Must Become a Recognized Medical Specialty
Why is primary care constrained in proactive prevention? A physician breaks down why healthspan medicine must become a recognized specialty, bridging evidence-based cardiology, exercise physiology, and geroscience.
THE HEALTHSPAN CLIMATEAug 9, 2026
What Is Healthspan Medicine? A Physician’s Framework for Evidence-Based Proactive Prevention
What is healthspan medicine? A physician breaks down evidence-based proactive prevention, how it differs from commercial longevity hype, and the 3 pillars of delaeMD.
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